Lamisil (generic name: terbinafine; brand names include: Tebina / Terbisil / Zabel) offers effective treatment for mild to severe nail fungus infection (including jock itch, athlete's foot and ringworm): high cure rates with low relapse, an established safety record, and convenient once-a-day dosing.
Lamisil is one of the most prescribed treatment for nail fungus infection worldwide. Since 1996, healthcare professionals have prescribed Lamisil to more than 17 million people in the U.S.
Less serious Lamisil side effects may include: Get emergency medical help if you have any of these signs of an allergic reaction to Lamisil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. The optimal clinical effect is seen some months after mycological cure and cessation of treatment. This is related to the period required for outgrowth of healthy nail. Get emergency medical help if you have any of these signs of an allergic reaction while taking terbinafine (the active ingredient contained in Lamisil) hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Metabolic Food Interactions cimetidine (Tagamet, Tagamet H; weight loss due to taste changes; http://edmedics.net/frblg/achat-clomid/#clomid-perte-blanche
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Lamisil (terbinafine) Tablets are supplied as white to yellow-tinged white circular, bi-convex, beveled tablets containing 250 mg of terbinafine imprinted with “LAMISIL (terbinafine) ” in circular form on one side and code “250” on the other. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. fever, chills, body aches, flu symptoms, sores in your mouth and throat; Storage And Handling This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
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fever, chills, body aches, flu symptoms, sores in your mouth and throat; Lamisil may also be used for purposes not listed in this medication guide. upset stomach, gas, diarrhea, mild nausea or stomach pain; Call your doctor at once if you have symptoms of liver damage, such as nausea, upper stomach pain, itching, loss of appetite, dark... Cardiovascular side effects have included vasculitis during postmarketing experience. Keep the Lamisil oral granules in their sealed packet until you are ready to use. Before taking Lamisil
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Postmarketing Experience What should I avoid while taking Lamisil? Less serious Lamisil side effects may include:
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Ocular side effects have included visual disturbance (1.1%). Changes in the ocular lens and retina have been reported; however, the clinical significance is unknown. Dyschromatopsia, whereby the patient reported a greenish hue in her vision, and photopsia have occurred in a patient after three weeks of therapy. This problem resolved within 1 week of discontinuing the drug. Reduced visual acuity and visual field defect have been reported during postmarketing experience. upset stomach, gas, diarrhea, mild nausea or stomach pain; The most frequently reported adverse events observed in the three US/Canadian placebo-controlled trials are listed in the table below. The adverse events reported encompass gastrointestinal symptoms (including diarrhea, dyspepsia, and abdominal pain), liver test abnormalities, rashes, urticaria, pruritus, and taste disturbances. Changes in the ocular lens and retina have been reported following the use of Lamisil (terbinafine) Tablets in controlled trials. The clinical significance of these changes is unknown. In general, the adverse events were mild, transient, and did not lead to discontinuation from study participation. a history of depression; or joint pain or swelling, swollen glands, patchy skin color, or a butterfly-shaped skin rash over your cheeks and nose; Renal In vivo studies have shown that terbinafine is an inhibitor of the CYP450 2D6 isozyme. Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. Coadministration of Lamisil (terbinafine) should be done with careful monitoring and may require a reduction in dose of the 2D6-metabolized drug. In a study to assess the effects of terbinafine on desipramine in healthy volunteers characterized as normal metabolizers, the administration of terbinafine resulted in a 2-fold increase in Cmax and a 5-fold increase in AUC. In this study, these effects were shown to persist at the last observation at 4 weeks after discontinuation of Lamisil (terbinafine) Tablets. In studies in healthy subjects characterized as extensive metabolizers of dextromethorphan, terbinafine increases the dextromethorphan/dextrorphan metabolite ratio in urine by 16- to 97-fold on average. In vitro studies with human liver microsomes showed that terbinafine does not inhibit the metabolism of tolbutamide, ethinylestradiol, ethoxycoumarin, cyclosporine, cisapride and fluvastatin. In vivo drug-drug interaction studies conducted in healthy volunteer subjects showed that terbinafine does not affect the clearance of antipyrine or digoxin. Terbinafine decreases the clearance of caffeine by 19%. Terbinafine increases the clearance of cyclosporine by 15%.