Chloroquine (brand names include: Aralen / Avloclor / Cadiquin / Chlorquin / Delagil / Emquin / Lagaquin / Malaquin / Malarex / Malarivon / Nivaquine / Resochin) is a drug of the aminoquinoline class.
Chloroquine is best known as a drug effective for the prevention as well as treatment of malaria. It is also used for the treatment of extraintestinal amebiasis.
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When doses are extended over a number of months, a slow onset of mood changes (i.e., depression, anxiety) can occur. These may be more pronounced with higher doses used for treatment. Chloroquine tablets have an unpleasant metallic taste. Uses Call911or other emergency services right away if you have: Antiviral Chloroquine has a very high volume of distribution, as it diffuses into the body's adipose tissue. Chloroquine and related quinines have been associated with cases of retinal toxicity, particularly when provided at higher doses for longer times. Accumulation of the drug may result in deposits that can lead to blurred vision and blindness. With long-term doses, routine visits to an ophthalmologist are recommended. Chloroquine is an effective medicine to prevent and treat a malaria infection caused by P. ovale or P. malariae parasites. But how well it works depends on how resistant the parasites are in the geographic location where the malaria infection occurred. Another serious side effect is toxicity to the eye (specifically, central serous retinopathy). This only occurs with long-term use over many years. Patients on long-term chloroquine therapy should be screened at baseline and every five years.[13] The daily safe maximum doses for eye toxicity can be computed from one's height and weight using this calculator.[14]
July 23 2025 13:01:34
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