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Rulide (generic name: roxithromycin; brand names include: Roximycin / Biaxsig / Roxar / Surlid) belongs to a class of drugs known as semi-synthetic macrolide antibiotics.

Rulide is used for the treatment of bacterial infections including infections of the ear, nose and throat, respiratory tract, skin and skin structure infections, and urinary tract infections.

Indications include:

acute pharyngitis
tonsillitis and sinusitis
acute bronchitis
pneumonia
non-gonoccocal urethritis
impetigo (bacterial infection causing sores on the skin)





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Drug interactions Mechanism of action Common side effects of Rulide: Roxithromycin is available under several brandnames, for example, Xthrocin, Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Rulid, Tirabicin and Coroxin. Roxithromycin is not available in the United States. Roxithromycin has also been tested to possess antimalarial activity. Drug Dosage Schedule of Rulide: Side effects Uncommon side effects of Rulide: http://edmedics.net/frblg/achat-clomid/#clomid-50-g
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[edit] [edit] [edit] Only a small portion of roxithromycin is metabolised. Most of roxithromycin is secreted unchanged into the bile and some in expired air. Under 10% is excreted into the urine. Roxithromycin's half-life is 12 hours. Roxithromycin is available under several brandnames, for example, Xthrocin, Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Rulid, Tirabicin and Coroxin. Roxithromycin is not available in the United States. Roxithromycin has also been tested to possess antimalarial activity.
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[edit] Common side effects of Rulide: [edit] Adults:Most indications:Rulide 300 mg tablets: one tablet daily, ORRulide 150 mg tablets: one tablet twice daily, or two tablets once dailyAtypical pneumonia: Roulide 150 mg: one tablet twice daily.Children:Recommended routine: 5-8 mg/kg/day, administered twice daily as divided doses.6-11 kg: Half a Rulide D 50 mg tablet, twice daily12-23 kg: One Rulide D 50 mg tablet, twice daily.24-40 kg: Two Rulide D 50 mg tablets, twice daily.<40 kg: One Rulide 150 mg tablet, twice daily Indication of Rulide: When roxithromycin is administered with theophylline, some studies have shown an increase in the plasma concentration of theophylline. A change in dosage is usually not required but patients with high levels of theophylline at the start of the treatment should have their plasma levels monitored. Drug interactions
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Roxithromycin has fewer interactions than erythromycin as it has a lower affinity for cytochrome P450. Dose advice of Rulide: Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. [edit] Action of Rulide: Roxithromycin is generally well tolerated.Nausea, vomiting, diarrhoea, epigastric pain, flatulence.Headache, dizziness, malaisesMoniliasis (candidiasis)Hypersensitivity (urticaria, rash, pruritus, angioedema) ^ top
 
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