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Gentamicin (brand names include: Gentak / Gentasol / Alcomicin / Diogent / Garamycin / Apigent / Biogaracin / Cidomycin / Diakarmon / Epigent / Garamicina / Genoptic / Gensumycin / Gentamen / Gentamytrex / Gentarad / Genticin / Genticyn / Optimycin) belongs to a group of medicines known as aminoglycoside antibiotics.

Indications include treatment of:

bone infections
respiratory tract infections
skin and soft tissue infections
abdominal and urinary tract infections
septicemia
infective endocarditis





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Native valve or prosthetic valve infections due to susceptible enterococci: Other side effects possibly related to gentamicin have included transient splenomegaly and fever. Parkinson's disease; or Native valve or prosthetic valve infections due to susceptible enterococci: 2 to 2.5 mg/kg loading dose, followed by 1.7 to 2 mg/kg IV every 8 hours 1 mg/kg IV or IM every 8 hours, in combination with ampicillin-sulbactam or vancomycin. loss of appetite; Duration: Therapy should be continued for at least 10 to 14 days, or until 3 days post acute inflammation, depending on the nature and severity of the infection. For severe infections, such as diabetic soft tissue infections, 14 to 21 days of therapy may be required. Limiting the duration of gentamicin therapy may help limit toxicity. Once the patient is stable for at least 48 hours, less toxic intravenous or oral antibiotic therapy may be considered according to microbiology sensitivity data. clomid x tren
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Gentamicin is an antibiotic. It fights bacteria in the body. What should I discuss with my healthcare provider before using gentamicin? Gentamicin is one of the few heat-stable antibiotics that remain active even after autoclaving, which makes it particularly useful in the preparation of some microbiological growth media. It is used during orthopaedic surgery when high temperatures are required for the setting of cements (e.g. hip replacements). Duration: 4 to 6 weeks, depending on the nature and severity of the infection. Chronic osteomyelitis may require an additional 1 to 2 months of oral antibiotics. Limiting the duration of gentamicin therapy may help limit toxicity. Once the patient is stable for at least 48 hours, less toxic intravenous or oral antibiotic therapy may be considered according to microbiology sensitivity data. In case of emergency/overdose
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Prosthetic valve infections due to staphylococci: Usual Adult Dose for Bacterial Endocarditis Prophylaxis: kidney disease; Usual Adult Dose for Cystic Fibrosis: Other side effects possibly related to gentamicin have included transient splenomegaly and fever. dizziness, clumsiness, or unsteadiness; 1.5 mg/kg IV or IM once within 30 minutes of starting the procedure. For high risk patients, in addition to gentamicin, ampicillin 50 mg/kg (maximum 2 G) is given IV or IM 30 minutes prior to the procedure, followed by ampicillin 25 mg/kg IV/IM or amoxicillin 25 mg/kg orally 6 hours later. In penicillin-allergic patients, vancomycin 20 mg/kg IV is infused over 1 to 2 hours instead of ampicillin/amoxicillin.
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If you are receiving gentamicin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible: Usual Pediatric Dose for Surgical Prophylaxis: Nervous system side effects have included ototoxicity, which generally presents as loss of vestibular function secondary to hair cell damage, but may also be auditory. Ototoxicity is closely related to the development of renal impairment, and may be irreversible. Peripheral neuropathy or encephalopathy with numbness, skin tingling, muscle twitching, seizures, and myasthenia gravis-like syndrome have also been reported.

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In case of emergency/overdose Gentamicin can also be highly nephrotoxic, particularly if multiple doses accumulate over a course of treatment. For this reason gentamicin is usually dosed by body weight. Various formulae exist for calculating gentamicin dosage. Also trough and peak serum levels of gentamicin are monitored during treatment, generally before and after the third dose is infused. [edit] Gentamicin eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. severe watery diarrhea and abdominal cramps. Difficulty multi-tasking, particularly when standing Ringing in the ears (tinnitus)