Írta: jefanaenly - Dátum: 02-12-2012 08:42
#1
Vancomycin (brand names include: Vanlid / Vancocin) is an antibiotic used to treat colitis (inflammation of the intestine).
Vancomycin belongs to a class of medications called glycopeptide antibiotics. It works by killling bacteria in the intestines.
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Cardiovascular Hepatic Do not take this medication if you are allergic to vancomycin. Vancomycin may induce antineutrophilic antibodies. A 48-year-old male developed neutropenia and positive antineutrophilic antibodies after 16 days of vancomycin. His WBC decreased to 600 cells/mm3 but recovered after discontinuation of vancomycin and initiation of granulocyte-colony stimulating factor. Vancomycin Injection, USP in the GALAXY plastic container (PL 2040) is a frozen, isoosmotic, sterile, nonpyrogenic premixed 100 mL, 150 mL, or 200 mL solution containing 500 mg, 750 mg, or 1 g Vancomycin respectively as Vancomycin hydrochloride. Each 100 mL of solution contains approximately 5 g of Dextrose Hydrous, USP. The pH of the solution may have been adjusted with hydrochloric acid and/or sodium hydroxide. Thawed solutions have a pH in the range of 3.0 to 5.0. After thawing to room temperature, this solution is intended for intravenous use only. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. The incidence of peripheral edema associated with the oral formulation was higher in patients older than 65 years of age than in patients 65 years of age or younger. If you have any of these other conditions, you may need a dose adjustment or special tests to safely take vancomycin:
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Do not refreeze thawed antibiotics. Metabolic Musculoskeletal hearing loss, ringing in your ears; The incidences of vomiting and constipation associated with the oral formulation were higher in patients older than 65 years of age than in patients 65 years of age or younger.
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Respiratory side effects have included at least one case of interstitial pneumonia. Vancomycin Injection, USP in the GALAXY plastic container (PL 2040) is a frozen, isoosmotic, sterile, nonpyrogenic premixed 100 mL, 150 mL, or 200 mL solution containing 500 mg, 750 mg, or 1 g Vancomycin respectively as Vancomycin hydrochloride. Each 100 mL of solution contains approximately 5 g of Dextrose Hydrous, USP. The pH of the solution may have been adjusted with hydrochloric acid and/or sodium hydroxide. Thawed solutions have a pH in the range of 3.0 to 5.0. After thawing to room temperature, this solution is intended for intravenous use only. Respiratory Before using vancomycin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Genitourinary side effects associated with the oral formulation have included urinary tract infection (8%). Use sterile equipment. The incidence of hypokalemia associated with the oral formulation was higher in patients older than 65 years of age than in patients 65 years of age or younger.
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Patients With Normal Renal Function The incidence of peripheral edema associated with the oral formulation was higher in patients older than 65 years of age than in patients 65 years of age or younger. Hypersensitivity side effects have included erythema multiforme, exfoliative dermatitis, linear IgA bullous dermatosis, Stevens-Johnson syndrome, and anaphylaxis. Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) has been reported with intravenous vancomycin during postmarketing experience. Anaphylaxis associated with vancomycin administration has been reported during postmarketing experience.
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Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, hearing problems, stomach/intestinal problems (e.g., inflammatory disorders of the intestines). feeling light-headed, fainting; The incidence of anemia associated with the oral formulation was higher in patients older than 65 years of age than in patients 65 years of age or younger. Musculoskeletal Hematologic Hepatic side effects have included elevated aspartate transaminase (AST) and alanine transaminase (ALT) with oral vancomycin in at least one case report. Abnormal liver function has been reported during intravenous administration. Vancomycin has been reported to be effective alone or in combination with an aminoglycoside for endocarditis caused by Streptococcus viridans or S. bovis. For endocarditis caused by enterococci (e.g., E. faecalis), vancomycin has been reported to be effective only in combination with an aminoglycoside.