Csatlakozott: 2014.09.08. Hétfő 20:00
Tartózkodási hely: Chile
|Patients treated with both dosing regimens of ixekizumab had significantly greater levels of fell allowance compared to placebo and to etanercept at the 12-week endpoint. Peel clearance was unhurried via guide essential endpoints in requital for psoriasis studies: the Psoriasis Area and Severity Index (PASI) and the Stagnant Physician Global Assessment (sPGA).
For patients treated with ixekizumab either every four weeks or every two weeks, between 78 to 90 percent of patients achieved at least a 75 percent reduction in PASI accompaniment (PASI 75) at 12 weeks. Additionally, 31 to 41 percent of these patients achieved PASI 100, or clear skin, at week 12. For likeness, between 5 to 7 percent of patients treated with etanercept in the UNCOVER-2 and 3 studies achieved PASI 100.
Statistically consequential improvements in pellicle hole measures as a replacement for patients treated with ixekizumab were observed as inopportune as the beginning week when compared to either placebo or etanercept, and continued in the course week 12. In the UNCOVER-1 learning, high levels of effect were maintained into done with 60 weeks of treatment.
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