in people could also lengthen life,
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. Too impatient to wait for Food and Drug Administration approval for clinical trials in people,
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, Parrish went to Colombia to test her company’s antiaging gene therapy on herself.

An intravenous infusion delivered viruses carrying a gene for a telomere-lengthening enzyme into her bloodstream. The gene therapy was also designed to inhibit action of the myostatin gene,
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, which stops muscle cells from growing. Inhibiting that gene may allow muscles to better repair themselves. Parrish said she had “myriad injections we didn’t even count — we would have lost count if we had” — into her muscles and other parts of her body. Her aim was to demonstrate that the therapy is safe. “I felt like we really had to take the first risk,
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,” she says.

In April,
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, BioViva reported in a news release that telomeres in Parrish’s white blood cells were longer,
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, now consistent with those of a 45-year-old instead of those of a retiree. No one knows how the treatment will affect Parrish’s health or life span. Some scientists say her risk of cancer may increase,
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, a concern the company dismisses.

“It’s absolutely premature” to conduct telomere therapy in people,
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, says Matt Kaeberlein, a geroscientist at the University of

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Algal toxin impairs sea lion memory By Sarah Zielinski ,
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, 13:49 PM December 16, 2015 SAN FRANCISCO – There is no locally caught crab on the menu here. The state of California warned earlier this year that the crustaceans may have high levels of domoic acid ,
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, a powerful neurotoxin, and should not be eaten. Domoic acid is produced by algae in the genus Pseudo-nitzschia ,
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, and there’s a huge bloom of them off the coast. The toxin accumulates in creatures that eat the algae, such as crabs, and on up the food chain. A person who eats one of these critters can get a potentially deadly... Source URL:

Psychology got rocked last year by a report that many of the field’s published results vanish in repeat experiments. But that disturbing study sounded a false alarm,
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, a controversial analysis finds.
The original investigation of 100 studies contained key errors,
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, contend Harvard University psychologist Daniel Gilbert and his colleagues. After correcting for those errors, the effects reported in 85 of those studies appeared in replications conducted by different researchers. So an initial conclusion that only 35 studies generated repeatable findings was a gross underestimate,
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, Gilbert’s team reports in the March 4 Science,
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.
“There’s no evidence for a replication crisis in psychology,
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,” Gilbert says.
Psychologist Brian Nosek of the University of Virginia in Charlottesville

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