Interpret with caution,
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Most scientists working on aging urge caution in extrapolating promising results in animal studies to humans. For instance,
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, one of the most promising early candidates for a rejuvenation factor from young blood was a protein called GDF11. Reports in 2013 and 2014 concluded that GDF11 levels in blood decline with age; restoring the protein in old animals could reverse some heart problems, improve muscle strength and spur nerve cell growth in the brain. ?Since those reports,
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, other researchers have disputed the protein’s revitalizing powers. In a recent study, researchers measured GDF11 levels in 140 people aged 21 to 93. Levels of the protein didn’t decline with age, Mayo Clinic researchers reported in the June 14 Cell Metabolism. Previous researchers may have gotten GDF11 mixed up with a similar protein called myostatin, which does dip as people get older. Not only does GDF11 not decline with age, having too much of it could be bad,
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, the Mayo team found. People with higher blood levels of the protein were more likely to be frail,
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, have diabetes and heart problems, and have a more difficult time recovering from surgery than people with lower levels of the protein.
Beyond the blood experiments,
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, scientists have examined various ideas about what goes wrong in aging and have devised strategies to counteract it. For instance,
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, some evidence suggests that stem cells run out of steam as they get older. Restoring old stem cells to youthful vigor may enable them to repair or replace damaged tissues and turn back the biological clock. Keeping stem cells youthful may involve sheltering them from inflammation or things that could damage their DNA,
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Fast radio bursts have stumped astronomers since the first one was reported in 2007 (SN: 8/9/14, p. 22). Since then, 17 more bursts have been detected by several radio telescopes around the world. In nearly every case, the outburst lasted just a few milliseconds and was never seen again. Only one,
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, first detected at the Arecibo Observatory in Puerto Rico in 2012, has been seen multiple times (SN Online: 12/21/16),
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Most radio telescopes can provide only a fuzzy idea of where on the sky a burst comes from. But the repetitive nature of this burst, dubbed FRB 121102, gave astronomers a heads up of where to point the Very Large Array,
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, a network of radio dishes near Socorro,
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, N.M., which could provide a sharper image.
“We have imaged the burst itself with the VLA and pinpointed where it is on the sky,
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,” said Shami Chatterjee,
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, an astrophysicist at Cornell University. Over the span of six months,
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, the VLA detected nine outbursts coming from the same direction as previous repetitions. A persistent glow of radio waves also comes from the same spot. Further observations with the Gemini telescope in Hawaii revealed that the radio outbursts coincide with a faint galaxy. By measuring how much the expansion of the universe has stretched the light coming from the galaxy,
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, the researchers were able to measure the distance to the source of the burst.
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