.jpg" style="width: 350px; height: 350px; float: right;" title="<b>DENTAL DNA</b> A hominid tooth from a 430,000-year-old Spanish cave site yielded gene fragments that helped researchers identify the tooth as having belonged to a Neandertal. ~~ Max Planck Institute for Evolutionary Anthropology" />
An ancient genetic puzzle has also emerged at Sima de los Huesos. On one hand, nuclear DNA — which passes from both parents to their children — pegs the Spanish hominids as Neandertals. But mitochondrial DNA — typically inherited only from the mother — already extracted from one Sima de los Huesos fossil (SN: 12/28/13, p. and described for a second fossil in the new study has more in common with Denisovans.
Denisovans lived in East Asia at least 44,
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,000 years ago, but their evolutionary history is unknown.
If early Neandertals lived in northern Spain roughly 430,
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,000 years ago,
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, “we have to go back further in time to reach the common ancestor of Neandertals and Denisovans,
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,” Meyer says.
The new genetic data from Sima de los Huesos now suggest that Denisovans split from Neandertals perhaps 450,000 years ago, says paleoanthropologist Chris Stringer of the Natural History Museum in London. Genetic and fossil evidence point to Neandertals and H,
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. sapiens diverging from a common ancestor around 650,
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,000 years ago,
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, he proposes.
But it’s hard to say whether that common ancestor was H. heidelbergensis, Stringer adds. “Research must refocus on fossils from 400,000 to 800,
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,000 years ago to determine which ones might

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