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08.03.2017, 11:48 - nieeshoes - Rank 6 - 1159 Posts
described online November 3 in Current Biology,
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, is “absolutely superb,” says neuroscientist Eric Kandel of Columbia University. “It fills in a lot of missing pieces.”
People possess a version of the Orb2 protein called CPEB,
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, a commonality that suggests memory might work in a similar way in people,
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, Kandel says. It’s not yet known whether people rely on the prion to store long-term memories. “We can’t be sure, but it’s very suggestive,” Kandel says.
When neuroscientist Kausik Si and colleagues used a genetic trick to inactivate Orb2 protein,
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, male flies were worse at remembering rejection. These lovesick males continued to woo a nonreceptive female long past when they should have learned that courtship was futile. In different tests,
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, these flies also had trouble remembering that a certain odor was tied to food.

Memory task,
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Male flies fed a drug that interfered with the memory protein Orb2 (blue bar, right) were worse at remembering not to woo an unreceptive female than flies that didn’t get the drug (gray bar,
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, left). Memory index represents the effect of training on recognizing courtship behavior; the higher the number,
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, the better the memory.


/sites/default/files/2016/11/main/articles/110316_LS-memory-protein-graph_inline.png


Si and colleagues found a different

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