Feline panleukopenia, more commonly known as feline distemper,
is a viral infection affecting
cats caused by feline
parvovirus,
a close relative of
canine parvovirus. It is not related to canine distemper. Protection is offered
by commercial feline distemper vaccine, which is usually a mixture of vaccines for several different diseases, including panleukopenia.
It is spread from one cat to another in a variety of ways: any contact with
an infected cat's bodily fluids or
feces can do the
trick, even sharing the same water dish.
The virus primarily attacks the lining of the
gastrointestinal tract, causing internal ulceration and, ultimately, total
sloughing of the intestinal epithelium. This results in profuse, usually bloody
diarrhea, causing severe dehydration, malnutrition, anemia, and often death.
The virus causes a decrease in the cat's
white blood cells, thus compromising its immune system. Typically, infection
causes a decrease in WBC, hematocrit and platelet counts on a CBC. This is often key in diagnosing panleukopenia.
Symptoms include
depression, lethargy, loss of appetite, a high fever, vomiting,
diarrhea, and loss of skin elasticity.
If a pregnant cat is exposed during pregnancy, the virus can cause
cerebellar hypoplasia in her offspring. This is why administering modified
live feline panleukopenia vaccine during pregnancy is discouraged.