Estradiol cream side effects may include headache, breast tenderness, nausea, and bloating. Some may experience mood swings, vaginal irritation, or changes in sexual desire. In rare cases, severe side effects like chest pain, vision changes, or allergic reactions may occur. Consult a doctor if you have a history of certain health conditions or experience concerning symptoms while using the cream.
Consult a doctor if you have a history of certain health conditions or experience concerning symptoms while using the cream. Estradiol cream, a hormone replacement therapy, may cause side effects like breast tenderness, nausea, headache, and skin irritation. It could also increase the risk of blood clots, stroke, and certain cancers. Consult a healthcare professional before use, especially if you have a history of these conditions or are at risk.