“We found dramatic changes everywhere in the brain,
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,” said study coauthor Jan-Marino Ramirez. Mice that had been stimulated had fewer newborn nerve cells in the hippocampus,
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, a brain structure important for learning and memory,
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, than unstimulated mice,
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, Ramirez said. The stimulation also made certain nerve cells more active in general.
Stimulated mice also displayed behaviors similar to some associated with ADHD in children. These mice were noticeably more active and had trouble remembering whether they had encountered an object. The mice also seemed more inclined to take risks,
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, venturing into open areas that mice normally shy away from, for instance.
Some of these results have been reported previously by the Seattle researchers, who have now replicated the findings in a different group of mice. Ramirez and colleagues are extending the work by looking for more detailed behavioral changes.
For instance,
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, preliminary tests have revealed that the mice are impatient and have trouble waiting for rewards. When given a choice between a long wait for a good reward of four food pellets and a short wait for one pellet, stimulated mice were more likely to go for the instant gratification than non-stimulated mice, particularly as wait times increased.
Overstimulation didn’t have the same effects on adult mice, a result that suggests the stimulation had a big influence on the developing — but not fully formed — brain.
If massive amounts of audio and visual stimulation do harm the growing brain, parents need to ponder how their children should interact with screens. So far,
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, though,
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, the research is too preliminary to change guidelines (SN Online: 10/23/16).

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