have smaller-than-normal brains. The results draw a direct link between Zika infection and microcephaly,
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, the authors write.
Article continues below

An even stronger link comes from Fernanda Cugola of the University of Sa?o Paulo in Brazil and colleagues. They infected a strain of mice called SJL with the Brazilian Zika virus — and the researchers didn’t have to tinker with the mice’s immune systems to do it. InfectedSJL mice then transmitted the virus from placenta to pups,
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, and newborn animals showed signs of microcephaly,
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, Cugola’s team reports in Nature,
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. But mice of a genetically different strain,
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, called C57BL/6,
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, resisted Zika’s brain-damaging handiwork.
The results suggest genetic differences could help explain why Zika strikes the babies of some pregnant women but not others,
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, the authors propose.
The U.S,
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. Centers for Disease Control and Prevention had officially confirmed the link between Zika and microcephaly

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