. These fragments can bind to receptors for opioid molecules in the brain.
But “just because something activates your opioid system doesn’t make it addictive,” Gearhardt cautions. A 2009 scientific report on casomorphins from the European Food Safety Authority stated that it’s unknown whether these molecules escape from the gastrointestinal track in large amounts,
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, or that they can get into the brain, though it is possible. When injected directly into animals, either into the body cavity or the brain, casomorphins did produce some effects such as pain relief and learning delays in newborn mice. But the peptide was also estimated to be 20 times less potent than morphine. In a 1994 dairy-funded study, rats were given casomorphin or morphine and placed in different chambers,
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, allowing them to associate the drug with a particular chamber. After several days,
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, researchers looked at which chamber the rats preferred to spend time in,
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, a common test of the rewarding properties of drugs such as morphine. While the rats were glad to spend time in a chamber associated with morphine as compared to water,
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, casomorphin produced no response.
“Understanding how food is rewarding and how it might overlap with addictive drugs is an interesting question,” Kalivas says. “Studies like this,
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, to me, kind of state the obvious. Food that’s palatable,
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, people will find more problematic.”
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