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GOING GLOBAL ?An antibiotic-resistant gene, mrc-1, had cropped up in a number of countries across the globe by March 1, 2016. Now,
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, scientists have found E. coli bacteria carrying the gene in the United States,
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, too.?

R.L. Skov and D.L. Monnet/
Eurosurveillance 2016



In December, Skov and colleagues discovered a Danish patient carrying bacteria with mcr-1 plasmid DNA, like the woman in Pennsylvania. And in November of 2015, researchers reported something similar in China.
Until then, all known colistin resistance was due to tweaks in chromosomal DNA (which, unlike plasmid DNA, isn’t easily spread among bacteria),
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, says Skov, of the Statens Serum Institut in Copenhagen,
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, who was not involved with the new work.
Colistin,
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, a 50-year-old drug that doctors largely stopped prescribing in the 1970s because of its side effects,
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, has made a comeback in the last five to 10 years. It’s used when other antibiotics fail; it’s a treatment option for people infected with multidrug-resistant bacteria. Now,
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, with colistin-resistant bacteria, Skov says, antibiotic treatment options are becoming more and more limited.
The problem, scientists have been pointing out for years, is that people

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