the brain might one day help scientists repair brains,
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, says coauthor of one of the studies?Gilad Barnea of Brown University in Providence,
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, R.I.
Unlike most places in the brain,
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, the olfactory system is constantly replenished with a steady stream of newborn neurons. To tell the brain what the nose has smelled, these newbies must send message-sending tendrils called axons to very specific blobs of neural tissue called glomeruli. Each neuron carries one type of odor-detecting protein,
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, which determines the axon’s final destination.
Those destinations can be disrupted when certain neurons are engineered to contain a different odor-sensing protein,
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, Barnea and Lulu Tsai of Drexel University in Philadelphia found in one of the studies,
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. This engineered odor-sensing molecule was a bad influence: It incited other neurons’ axons to go to the wrong glomeruli. Researchers don’t know whether this mistake affected the animals’ sense of smell.
The axons were vulnerable to diversion only for a brief window of time,
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, Barnea and Tsai found. When the engineered odor-sensing molecule was produced right after birth,
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, one mouse of nine laid down faulty wiring. When the molecule was

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